Ligand-stimulated signaling events in immature CD4+CD8+ thymocytes expressing competent T-cell receptor complexes.

During thymic selection of the developing T-cell repertoire, the fate of individual CD4+CD8+ thymocytes is determined by the specificity of the T-cell antigen receptors (TCRs) they express. Paradoxically, most CD4+CD8+ thymocytes express few TCR molecules, and those they express are essentially inca...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Nakayama, T, Samelson, L E, Nakayama, Y, Munitz, T I, Sheard, M, June, C H, Singer, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52844/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1719558/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.22.9949
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