Tyrosine kinase activity of CD4-associated p56lck may not be required for CD4-dependent T-cell activation.
The lymphoid-specific tyrosine kinase p56lck (Lck) is critical for the development and activation of T lymphocytes, and Lck kinase activity has been implicated in both T-cell antigen receptor/CD3- and CD4-mediated signaling. CD4-dependent T-cell activation has been demonstrated to be dependent upon...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48089/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7505449/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.24.11885 |
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