E-protein–regulated expression of CXCR4 adheres preselection thymocytes to the thymic cortex

Preselection thymocytes are normally retained in the thymic cortex, but the mechanisms responsible remain incompletely understood. We now report that deletion of genes encoding the E-protein transcription factors E2A and HEB disorders chemokine receptor expression on developing thymocytes to allow e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Med
Prif Awduron: Kadakia, Tejas, Tai, Xuguang, Kruhlak, Michael, Wisniewski, Jan, Hwang, Il-Young, Roy, Sumedha, Guinter, Terry I., Alag, Amala, Kehrl, John H., Zhuang, Yuan, Singer, Alfred
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2019
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683992/
https://ncbi.nlm.nih.gov/pubmed/31201207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20182285
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