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An effective mouse model for adoptive cancer immunotherapy targeting neoantigens
The adoptive cell transfer (ACT) of T cells targeting mutated neoantigens can cause objective responses in varieties of metastatic cancers, but the development of new T cell–based treatments relies on accurate animal models. To investigate the therapeutic effect of targeting a neoantigen with ACT, w...
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| Udgivet i: | JCI Insight |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6542630/ https://ncbi.nlm.nih.gov/pubmed/31092734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124405 |
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