Cancer vaccines: progress reveals new complexities

by Yu, Zhiya, Restifo, Nicholas P.
Published 2002

Therapeutic cancer vaccines: are we there yet?

by Klebanoff, Christopher A., Acquavella, Nicholas, Yu, Zhiya, Restifo, Nicholas P.
Published 2011

The in vivo expansion rate of properly stimulated transferred CD8(+) T cells exceeds that of an aggressively growing mouse tumor

by Hwang, Leroy N., Yu, Zhiya, Palmer, Douglas C., Restifo, Nicholas P.
Published 2006

Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells

by Kochenderfer, James N., Yu, Zhiya, Frasheri, Dorina, Restifo, Nicholas P., Rosenberg, Steven A.
Published 2010

An In Vivo Mouse Model of Metastatic Human Thyroid Cancer

by Zhang, Lisa, Gaskins, Kelli, Yu, Zhiya, Xiong, Yin, Merino, Maria J., Kebebew, Electron
Published 2014

An effective mouse model for adoptive cancer immunotherapy targeting neoantigens

by Hanada, Ken-ichi, Yu, Zhiya, Chappell, Gabrielle R., Park, Adam S., Restifo, Nicholas P.
Published in JCI Insight (2019)

Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design

by Borbulevych, Oleg Y., Baxter, Tiffany K., Yu, Zhiya, Restifo, Nicholas P., Baker, Brian M.
Published 2005

Simultaneous Targeting of Tumor Antigens and the Tumor Vasculature using T Lymphocyte Transfer Synergize to Induce Regression of Established Tumors in Mice

by Chinnasamy, Dhanalakshmi, Tran, Eric, Yu, Zhiya, Morgan, Richard A., Restifo, Nicholas P., Rosenberg, Steven A.
Published 2013

Programming tumor-reactive effector memory CD8(+) T cells in vitro obviates the requirement for in vivo vaccination

by Klebanoff, Christopher A., Yu, Zhiya, Hwang, Leroy N., Palmer, Douglas C., Gattinoni, Luca, Restifo, Nicholas P.
Published 2009

Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer

by Shrimali, Rajeev K., Yu, Zhiya, Theoret, Marc R., Chinnasamy, Dhanalakshmi, Restifo, Nicholas P., Rosenberg, Steven A.
Published 2010

Identification of T-cell Receptors Targeting KRAS-mutated Human Tumors

by Wang, Qiong J., Yu, Zhiya, Griffith, Kayla, Hanada, Ken-ichi, Restifo, Nicholas P., Yang, James C.
Published in Cancer Immunol Res (2015)

Characterization of Genetically Modified T-Cell Receptors that Recognize the CEA:691-699 Peptide in the Context of HLA-A2.1 on Human Colorectal Cancer Cells

by Parkhurst, Maria R., Joo, Jayne, Riley, John P., Yu, Zhiya, Li, Yong, Robbins, Paul F., Rosenberg, Steven A.
Published 2009

Pre-clinical Evaluation of Chimeric Antigen Receptors Targeting CD70-Expressing Cancers

by Wang, Qiong J., Yu, Zhiya, Hanada, Ken-ichi, Patel, Krishna, Kleiner, David, Restifo, Nicholas P., Yang, James C.
Published in Clin Cancer Res (2016)

Local Delivery of lnterleukin-12 Using T Cells Targeting VEGF Receptor-2 Eradicates Multiple Vascularized Tumors in Mice

by Chinnasamy, Dhanalakshmi, Yu, Zhiya, Kerkar, Sid P., Zhang, Ling, Morgan, Richard A., Restifo, Nicholas P., Rosenberg, Steven A.
Published in Clin Cancer Res (2012)

In vitro generated anti-tumor T lymphocytes exhibit distinct subsets mimicking in vivo antigen experienced cells

by Yang, Shicheng, Gattinoni, Luca, Liu, Fang, Ji, Yun, Yu, Zhiya, Restifo, Nicholas P., Rosenberg, Steven A., Morgan, Richard A.
Published 2011

Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia

by Tran, Eric, Chinnasamy, Dhanalakshmi, Yu, Zhiya, Morgan, Richard A., Lee, Chyi-Chia Richard, Restifo, Nicholas P., Rosenberg, Steven A.
Published 2013

Modulating the differentiation status of ex vivo-cultured anti-tumor T cells using cytokine cocktails

by Yang, Shicheng, Ji, Yun, Gattinoni, Luca, Zhang, Ling, Yu, Zhiya, Restifo, Nicholas P., Rosenberg, Steven A., Morgan, Richard A.
Published in Cancer Immunol Immunother (2012)

Enhanced efficacy and limited systemic cytokine exposure with membrane-anchored interleukin-12 T-cell therapy in murine tumor models

by Zhang, Ling, Davies, John S, Serna, Carylinda, Yu, Zhiya, Restifo, Nicholas P, Rosenberg, Steven A, Morgan, Richard A, Hinrichs, Christian S
Published in J Immunother Cancer (2020)

Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8(+) T cells

by Wrzesinski, Claudia, Paulos, Chrystal M., Gattinoni, Luca, Palmer, Douglas C., Kaiser, Andrew, Yu, Zhiya, Rosenberg, Steven A., Restifo, Nicholas P.
Published 2007

Improving Adoptive T Cell Therapy by Targeting and Controlling IL-12 Expression to the Tumor Environment

by Zhang, Ling, Kerkar, Sid P, Yu, Zhiya, Zheng, Zhili, Yang, Shicheng, Restifo, Nicholas P, Rosenberg, Steven A, Morgan, Richard A
Published 2011