Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice

Immunotherapies based on adoptive cell transfer are highly effective in the treatment of metastatic melanoma, but the use of this approach in other cancer histologies has been hampered by the identification of appropriate target molecules. Immunologic approaches targeting tumor vasculature provide a...

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Detalhes bibliográficos
Main Authors: Chinnasamy, Dhanalakshmi, Yu, Zhiya, Theoret, Marc R., Zhao, Yangbing, Shrimali, Rajeev K., Morgan, Richard A., Feldman, Steven A., Restifo, Nicholas P., Rosenberg, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964987/
https://ncbi.nlm.nih.gov/pubmed/20978347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43490
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