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Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer

Adoptive cell transfer (ACT) – based immunotherapies can mediate objective cancer regression in animal models and in up to 70% of patients with metastatic melanoma but it remains unclear whether the tumor vasculature impedes the egress of tumor specific T cells thus hindering this immunotherapy. Dis...

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Dettagli Bibliografici
Autori principali: Shrimali, Rajeev K., Yu, Zhiya, Theoret, Marc R., Chinnasamy, Dhanalakshmi, Restifo, Nicholas P., Rosenberg, Steven A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912959/
https://ncbi.nlm.nih.gov/pubmed/20631075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0153
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