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Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells
Lymphodepletion prior to adoptive cell transfer (ACT)-based immunotherapies can enhance anti-tumor responses by augmenting innate immunity, by increasing access to homeostatic cytokines, and by depressing the numbers of regulatory T cells and myeloid-derived suppressor cells. Although it is clear th...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3247626/ https://ncbi.nlm.nih.gov/pubmed/19952961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3181b88ffc |
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