Adoptive transfer of allogeneic tumor-specific T cells mediates effective regression of large tumors across major histocompatibility barriers

Graft-versus-tumor effects can be achieved after allogeneic bone marrow transplantation in patients with malignancies of the kidney or hematopoietic system but are often accompanied by severe graft-versus-host-disease (GVHD). We sought to maximize graft-versus-tumor while minimizing GVHD using tumor...

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Main Authors: Boni, Andrea, Muranski, Pawel, Cassard, Lydie, Wrzesinski, Claudia, Paulos, Chrystal M., Palmer, Douglas C., Gattinoni, Luca, Hinrichs, Christian S., Chan, Chi-Chao, Rosenberg, Steven A., Restifo, Nicholas P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2008
Ábhair:
Transplantation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597140/
https://ncbi.nlm.nih.gov/pubmed/18799724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-169797
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