Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8(+) T cells via TLR4 signaling

Lymphodepletion with total body irradiation (TBI) increases the efficacy of adoptively transferred tumor-specific CD8(+) T cells by depleting inhibitory lymphocytes and increasing homeostatic cytokine levels. We found that TBI augmented the function of adoptively transferred CD8(+) T cells in mice g...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Paulos, Chrystal M., Wrzesinski, Claudia, Kaiser,, Andrew, Hinrichs, Christian S., Chieppa, Marcello, Cassard, Lydie, Palmer, Douglas C., Boni, Andrea, Muranski, Pawel, Yu, Zhiya, Gattinoni, Luca, Antony, Paul A., Rosenberg, Steven A., Restifo, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924500/
https://ncbi.nlm.nih.gov/pubmed/17657310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32205
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados