Molecular Pathways: Breaking the Epithelial Cancer Barrier for Chimeric Antigen Receptor and T-cell Receptor Gene Therapy

Por Hinrichs, Christian S.
Publicado no Clin Cancer Res (2016)

Exploiting the curative potential of adoptive T-cell therapy for cancer

Por Hinrichs, Christian S., Rosenberg, Steven A.
Publicado em 2014

Reassessing target antigens for adoptive T cell therapy

Por Hinrichs, Christian S., Restifo, Nicholas P.
Publicado no Nat Biotechnol (2013)

Programming CD8(+) T cells for effective immunotherapy

Por Hinrichs, Christian S, Gattinoni, Luca, Restifo, Nicholas P
Publicado em 2006

Glucocorticoids Do Not Inhibit Antitumor Activity of Activated CD8(+) T Cells

Por Hinrichs, Christian S., Palmer, Douglas C., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2005

Adoptive transfer of tumor infiltrating lymphocytes for metastatic cervical cancer

Por Hinrichs, Christian S, Stevanovic, Sanja, Draper, Lindsey, Langhan, Michelle, Dudley, Mark, Wunderlich, John, Rosenberg, Steven A
Publicado em 2013

Adoptively transferred tumor-infiltrating T cells target somatic cancer mutations in a human papillomavirus+ cancer patient with complete tumor regression

Por Stevanović, Sanja, Anna, Pasetto, Gartner, Jared J, Tran, Eric, Robbins, Paul F, Rosenberg, Steven A, Hinrichs, Christian S
Publicado no J Immunother Cancer (2015)

Phenotype and Function of T Cells Infiltrating Visceral Metastases from Gastrointestinal Cancers and Melanoma: Implications for Adoptive Cell Transfer Therapy

Por Turcotte, Simon, Gros, Alena, Hogan, Katherine, Tran, Eric, Hinrichs, Christian S., Wunderlich, John R., Dudley, Mark E., Rosenberg, Steven A.
Publicado em 2013

Targeting of HPV-16+ epithelial cancer cells by TCR gene engineered T cells directed against E6

Por Draper, Lindsey M., Kwong, Mei Li, Gros, Alena, Stevanović, Sanja, Tran, Eric, Kerkar, Sid, Raffeld, Mark, Rosenberg, Steven A., Hinrichs, Christian S.
Publicado no Clin Cancer Res (2015)

Type 17 CD8(+) T cells display enhanced antitumor immunity

Por Hinrichs, Christian S., Kaiser, Andrew, Paulos, Chrystal M., Cassard, Lydie, Sanchez-Perez, Luis, Heemskerk, Bianca, Wrzesinski, Claudia, Borman, Zachary A., Muranski, Pawel, Restifo, Nicholas P.
Publicado em 2009

A high molecular weight-melanoma associated antigen-specific chimeric antigen receptor redirects lymphocytes to target human melanomas

Por Burns, William R., Zhao, Yangbing, Frankel, Timothy L., Hinrichs, Christian S., Zheng, Zhili, Xu, Hui, Feldman, Steven A., Ferrone, Soldano, Rosenberg, Steven A., Morgan, Richard A.
Publicado em 2010

IL-2 and IL-21 confer opposing differentiation programs to CD8(+) T cells for adoptive immunotherapy

Por Hinrichs, Christian S., Spolski, Rosanne, Paulos, Chrystal M., Gattinoni, Luca, Kerstann, Keith W., Palmer, Douglas C., Klebanoff, Christopher A., Rosenberg, Steven A., Leonard, Warren J., Restifo, Nicholas P.
Publicado em 2008

Adoptive transfer of allogeneic tumor-specific T cells mediates effective regression of large tumors across major histocompatibility barriers

Por Boni, Andrea, Muranski, Pawel, Cassard, Lydie, Wrzesinski, Claudia, Paulos, Chrystal M., Palmer, Douglas C., Gattinoni, Luca, Hinrichs, Christian S., Chan, Chi-Chao, Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2008

Wnt signaling arrests effector T cell differentiation and generates CD8(+) memory stem cells

Por Gattinoni, Luca, Zhong, Xiao-Song, Palmer, Douglas C, Ji, Yun, Hinrichs, Christian S, Yu, Zhiya, Wrzesinski, Claudia, Boni, Andrea, Cassard, Lydie, Church, Lindsay, Paulos, Chrystal M, Muranski, Pawel, Restifo, Nicholas P
Publicado em 2009

Determinants of successful CD8(+) T cell adoptive immunotherapy for large established tumors in mice

Por Klebanoff, Christopher A., Gattinoni, Luca, Palmer, Douglas C., Muranski, Pawel, Ji, Yun, Hinrichs, Christian S., Borman, Zachary A., Kerkar, Sid P., Scott, Christopher D., Finkelstein, Steven E., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2011

Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8(+) T cells via TLR4 signaling

Por Paulos, Chrystal M., Wrzesinski, Claudia, Kaiser,, Andrew, Hinrichs, Christian S., Chieppa, Marcello, Cassard, Lydie, Palmer, Douglas C., Boni, Andrea, Muranski, Pawel, Yu, Zhiya, Gattinoni, Luca, Antony, Paul A., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2007

Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8(+) T cells via TLR4 signaling

Por Paulos, Chrystal M., Wrzesinski, Claudia, Kaiser, Andrew, Hinrichs, Christian S., Chieppa, Marcello, Cassard, Lydie, Palmer, Douglas C., Boni, Andrea, Muranski, Pawel, Yu, Zhiya, Gattinoni, Luca, Antony, Paul A., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2007

Toll-like Receptors in Tumor Immunotherapy

Por Paulos, Chrystal M., Kaiser, Andrew, Wrzesinski, Claudia, Hinrichs, Christian S., Cassard, Lydie, Boni, Andrea, Muranski, Pawel, Sanchez-Perez, Luis, Palmer, Douglas C., Yu, Zhiya, Antony, Paul A., Gattinoni, Luca, Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2007

Synergy of IL-21 and IL-15 in regulating CD8(+) T cell expansion and function

Por Zeng, Rong, Spolski, Rosanne, Finkelstein, Steven E., Oh, SangKon, Kovanen, Panu E., Hinrichs, Christian S., Pise-Masison, Cynthia A., Radonovich, Michael F., Brady, John N., Restifo, Nicholas P., Berzofsky, Jay A., Leonard, Warren J.
Publicado em 2005

A Phase I study of an HLA-DPB1*0401-restricted T cell receptor targeting MAGE-A3 for patients with metastatic cancers

Por Lu, Yong-Chen, Parker, Linda, Lu, Tangying, Zheng, Zhili, Yao, Xin, Robbins, Paul F, van der Bruggen, Pierre, Klebanoff, Christopher A, Hinrichs, Christian S, Goff, Stephanie, Sherry, Richard, Kammula, Udai, Yang, James C, Rosenberg, Steven A
Publicado no J Immunother Cancer (2015)