Determinants of successful CD8(+) T cell adoptive immunotherapy for large established tumors in mice

PURPOSE: Adoptive cell transfer (ACT) of tumor-infiltrating or genetically engineered T cells can cause durable responses in patients with metastatic cancer. Multiple clinically-modifiable parameters can comprise this therapy, including cell dose and phenotype, in vivo antigen re-stimulation, and co...

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書誌詳細
主要な著者: Klebanoff, Christopher A., Gattinoni, Luca, Palmer, Douglas C., Muranski, Pawel, Ji, Yun, Hinrichs, Christian S., Borman, Zachary A., Kerkar, Sid P., Scott, Christopher D., Finkelstein, Steven E., Rosenberg, Steven A., Restifo, Nicholas P.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176721/
https://ncbi.nlm.nih.gov/pubmed/21737507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0503
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