Determinants of successful CD8(+) T cell adoptive immunotherapy for large established tumors in mice

PURPOSE: Adoptive cell transfer (ACT) of tumor-infiltrating or genetically engineered T cells can cause durable responses in patients with metastatic cancer. Multiple clinically-modifiable parameters can comprise this therapy, including cell dose and phenotype, in vivo antigen re-stimulation, and co...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Klebanoff, Christopher A., Gattinoni, Luca, Palmer, Douglas C., Muranski, Pawel, Ji, Yun, Hinrichs, Christian S., Borman, Zachary A., Kerkar, Sid P., Scott, Christopher D., Finkelstein, Steven E., Rosenberg, Steven A., Restifo, Nicholas P.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176721/
https://ncbi.nlm.nih.gov/pubmed/21737507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0503
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires