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Sorting through subsets: Which T cell populations mediate highly effective adoptive immunotherapy?

CD8(+) T cells have been described as being naïve (T(N)) or one of four antigen-experienced subtypes representing a continuum of differentiation and maturation: stem cell memory (T(SCM)), central memory (T(CM)), effector memory (T(EM)), and terminally differentiated effector T cells (T(EFF)). In mic...

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Detalhes bibliográficos
Main Authors: Klebanoff, Christopher A., Gattinoni, Luca, Restifo, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501135/
https://ncbi.nlm.nih.gov/pubmed/23090074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31827806e6
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