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Pharmacologic Induction of CD8(+) T Cell Memory: Better Living Through Chemistry

The generation of a robust population of memory T cells is critical for effective vaccine and cell-based therapies to prevent and treat infectious diseases and cancer. A series of recent papers have established a new, cell-intrinsic approach in which small molecules target key metabolic and developm...

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Hlavní autoři: Gattinoni, Luca, Klebanoff, Christopher A., Restifo, Nicholas P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241001/
https://ncbi.nlm.nih.gov/pubmed/20371454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000302
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