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Adoptive immunotherapy for cancer: building on success

Adoptive cell transfer after host preconditioning by lymphodepletion represents an important advance in cancer immunotherapy. Here, we describe how a lymphopaenic environment enables tumour-reactive T cells to destroy large burdens of metastatic tumour and how the state of differentiation of the ado...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gattinoni, Luca, Powell, Daniel J., Rosenberg, Steven A., Restifo, Nicholas P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1473162/
https://ncbi.nlm.nih.gov/pubmed/16622476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri1842
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