Genetic engineering of murine CD8+ and CD4+ T cells for pre-clinical adoptive immunotherapy studies

T-cell-receptor (TCR) gene therapy enables for the rapid creation of antigen-specific T cells from mice of any strain and represents a valuable tool for pre-clinical immunotherapy studies. Here, we describe the superiority of gamma-retroviral vectors compared to lentiviral vectors for transduction o...

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Detalhes bibliográficos
Main Authors: Kerkar, Sid P, Sanchez-Perez, Luis, Yang, Shicheng, Borman, Zachary, Muranski, Pawel, Ji, Yun, Chinnasamy, Dhanalakshmi, Kaiser, Andrew DM, Hinrichs, Christian, Klebanoff, Christopher A, Scott, Christopher, Gattinoni, Luca, Morgan, Richard A, Rosenberg, Steven A, Restifo, Nicholas P
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100770/
https://ncbi.nlm.nih.gov/pubmed/21499127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3182187600
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