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Reassessing target antigens for adoptive T cell therapy

Adoptive T cell therapy can target and kill widespread malignant cells thereby inducing durable clinical responses in melanoma and selected other malignances. However, many commonly targeted tumor antigens are also expressed by healthy tissues, and T cells do not distinguish between benign and malig...

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Dades bibliogràfiques
Publicat a:Nat Biotechnol
Autors principals: Hinrichs, Christian S., Restifo, Nicholas P.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280065/
https://ncbi.nlm.nih.gov/pubmed/24142051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2725
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