CD8(+) T-cell memory in tumor immunology and immunotherapy

Por Klebanoff, Christopher A., Gattinoni, Luca, Restifo, Nicholas P.
Publicado em 2006

Pharmacologic Induction of CD8(+) T Cell Memory: Better Living Through Chemistry

Por Gattinoni, Luca, Klebanoff, Christopher A., Restifo, Nicholas P.
Publicado em 2009

Sorting through subsets: Which T cell populations mediate highly effective adoptive immunotherapy?

Por Klebanoff, Christopher A., Gattinoni, Luca, Restifo, Nicholas P.
Publicado em 2012

Therapeutic cancer vaccines: are we there yet?

Por Klebanoff, Christopher A., Acquavella, Nicholas, Yu, Zhiya, Restifo, Nicholas P.
Publicado em 2011

Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy

Por Klebanoff, Christopher A, Khong, Hung T, Antony, Paul A, Palmer, Douglas C, Restifo, Nicholas P
Publicado em 2005

Programming tumor-reactive effector memory CD8(+) T cells in vitro obviates the requirement for in vivo vaccination

Por Klebanoff, Christopher A., Yu, Zhiya, Hwang, Leroy N., Palmer, Douglas C., Gattinoni, Luca, Restifo, Nicholas P.
Publicado em 2009

Fas expression in memory CD8+ T cell subsets augments cellular differentiation and effector function

Por Yamamoto, Tori, Leonardi, Anthony, Liu, Hui, Wang, Ena, Gattinoni, Luca, Cruz, Anthony, Ouyang, Claudia, Siegel, Richard, Restifo, Nicholas, Klebanoff, Christopher A
Publicado no J Immunother Cancer (2015)

Elevated potassium levels suppress T cell activation within tumors

Por Eil, Robert L, Roychoudhuri, Rahul, Clever, David, Patel, Shashank, Sukumar, Madhu, Pan, Jenny H, Palmer, Douglas, Klebanoff, Christopher A, Restifo, Nicholas P
Publicado no J Immunother Cancer (2015)

Induction of an acute vitamin A-deficient state following total body irradiation impairs anti-tumor immunity by altering the homeostasis of pre-cDC derived dendritic cells

Por Klebanoff, Christopher A, Spencer, Sean, Roychoudhuri, Rahu, Ji, Yun, Sukumar, Madhu, Muranski, Pawel, Napoli, Joseph L, Gattinoni, Luca, Belkaid, Yasmine, Restifo, Nicholas P
Publicado em 2013

Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8(+) T cells

Por Gattinoni, Luca, Klebanoff, Christopher A., Palmer, Douglas C., Wrzesinski, Claudia, Kerstann, Keith, Yu, Zhiya, Finkelstein, Steven E., Theoret, Marc R., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2005

Cish actively silences tcr signaling in CD8+ T cells to maintain tumor tolerance

Por Palmer, Douglas, Guittard, Geoff, Franco, Zulmarie, Patel, Shashank, Klebanoff, Christopher A, Sukumar, Madhusudhanan, Eil, Robert L, Clever, David, Balagopalan, Lakshmi, Roychoudhuri, Rahul, Samelson, Larry, Restifo, Nicholas
Publicado no J Immunother Cancer (2015)

Modulating immunometabolism of tumor specific mouse and human lymphocytes to enhance T cell based therapy for cancer

Por Sukumar, Madhusudhanan, Liu, Jie, Patel, Shashank J, Klebanoff, Christopher A, Mehta, Gautam, Roychoudhuri, Rahul, Crompton, Joseph, Clever, David, Gattinoni, Luca, Muranski, Pawel, Finkel, Toren, Restifo, Nicholas
Publicado no J Immunother Cancer (2015)

Interleukin-2-Dependent Mechanisms of Tolerance and Immunity In Vivo

Por Antony, Paul A., Paulos, Chrystal M., Ahmadzadeh, Mojgan, Akpinarli, Akgül, Palmer, Douglas C., Sato, Noriko, Kaiser, Andrew, Heinrichs, Christian, Klebanoff, Christopher A., Tagaya, Yutaka, Restifo, Nicholas P.
Publicado em 2006

IL-2 and IL-21 confer opposing differentiation programs to CD8(+) T cells for adoptive immunotherapy

Por Hinrichs, Christian S., Spolski, Rosanne, Paulos, Chrystal M., Gattinoni, Luca, Kerstann, Keith W., Palmer, Douglas C., Klebanoff, Christopher A., Rosenberg, Steven A., Leonard, Warren J., Restifo, Nicholas P.
Publicado em 2008

Immunotherapy generates selective pressure for acquisition of immunogenic neoantigens in escape tumors

Por Pan, Jenny H, Vodnala, Suman, Eil, Robert L, Yu, Zhiya, Gartner, Jared J, Clever, David, Roychoudhuri, Rahul, Patel, Shashank J, Klebanoff, Christopher A, Sukumar, Madhusudhanan, Yamamoto, Tori, Restifo, Nicholas P
Publicado no J Immunother Cancer (2015)

Determinants of successful CD8(+) T cell adoptive immunotherapy for large established tumors in mice

Por Klebanoff, Christopher A., Gattinoni, Luca, Palmer, Douglas C., Muranski, Pawel, Ji, Yun, Hinrichs, Christian S., Borman, Zachary A., Kerkar, Sid P., Scott, Christopher D., Finkelstein, Steven E., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2011

Central memory self/tumor-reactive CD8(+) T cells confer superior antitumor immunity compared with effector memory T cells

Por Klebanoff, Christopher A., Gattinoni, Luca, Torabi-Parizi, Parizad, Kerstann, Keith, Cardones, Adela R., Finkelstein, Steven E., Palmer, Douglas C., Antony, Paul A., Hwang, Sam T., Rosenberg, Steven A., Waldmann, Thomas A., Restifo, Nicholas P.
Publicado em 2005

Vaccine-Stimulated, Adoptively Transferred CD8(+) T Cells Traffic Indiscriminately and Ubiquitously while Mediating Specific Tumor Destruction

Por Palmer, Douglas C., Balasubramaniam, Sanjeeve, Hanada, Ken-ichi, Wrzesinski, Claudia, Yu, Zhiya, Farid, Shahram, Theoret, Marc R., Hwang, Leroy N., Klebanoff, Christopher A., Gattinoni, Luca, Goldstein, Allan L., Yang, James C., Restifo, Nicholas P.
Publicado em 2004

CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4 T helper cells and hindered by naturally occurring T regulatory cells.

Por Antony, Paul A., Piccirillo, Ciriaco A., Akpinarli, Akgül, Finkelstein, Steven E., Speiss, Paul J., Surman, Deborah R., Palmer, Douglas C., Chan, Chi-Chao, Klebanoff, Christopher A., Overwijk, Willem W., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2005

A Phase I study of an HLA-DPB1*0401-restricted T cell receptor targeting MAGE-A3 for patients with metastatic cancers

Por Lu, Yong-Chen, Parker, Linda, Lu, Tangying, Zheng, Zhili, Yao, Xin, Robbins, Paul F, van der Bruggen, Pierre, Klebanoff, Christopher A, Hinrichs, Christian S, Goff, Stephanie, Sherry, Richard, Kammula, Udai, Yang, James C, Rosenberg, Steven A
Publicado no J Immunother Cancer (2015)