Central memory self/tumor-reactive CD8(+) T cells confer superior antitumor immunity compared with effector memory T cells

Central memory CD8(+) T cells (T(CM)) and effector memory CD8(+) T cells (T(EM)) are found in humans and mice; however, their relative contributions to host immunity have only recently been examined in vivo. Further, the ability of T(CM) to treat an established tumor or infection has yet to be evalu...

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Detalhes bibliográficos
Main Authors: Klebanoff, Christopher A., Gattinoni, Luca, Torabi-Parizi, Parizad, Kerstann, Keith, Cardones, Adela R., Finkelstein, Steven E., Palmer, Douglas C., Antony, Paul A., Hwang, Sam T., Rosenberg, Steven A., Waldmann, Thomas A., Restifo, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1172264/
https://ncbi.nlm.nih.gov/pubmed/15980149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503726102
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