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Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8(+) T cells
Depleting host immune elements with nonmyeloablative regimens prior to the adoptive transfer of tumor-specific CD8(+) T cells significantly enhances tumor treatment. In the current study, superior antitumor efficacy was achieved by further increasing the intensity of lymphodepletion to a level that...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1783812/ https://ncbi.nlm.nih.gov/pubmed/17273561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30414 |
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