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Increased intensity lymphodepletion and adoptive immunotherapy—how far can we go?

In a recent clinical trial involving patients with metastatic melanoma, immunosuppressive conditioning with fludarabine and cyclophosphamide resulted in a 50% response rate and a robust long-term persistence of adoptively transferred T cells. Experimental findings indicate that lymphodepletion prior...

詳細記述

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書誌詳細
主要な著者: Muranski, Pawel, Boni, Andrea, Wrzesinski, Claudia, Citrin, Deborah E, Rosenberg, Steven A, Childs, Richard, Restifo, Nicholas P
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773008/
https://ncbi.nlm.nih.gov/pubmed/17139318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncponc0666
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