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Increased intensity lymphodepletion and adoptive immunotherapy—how far can we go?
In a recent clinical trial involving patients with metastatic melanoma, immunosuppressive conditioning with fludarabine and cyclophosphamide resulted in a 50% response rate and a robust long-term persistence of adoptively transferred T cells. Experimental findings indicate that lymphodepletion prior...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1773008/ https://ncbi.nlm.nih.gov/pubmed/17139318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncponc0666 |
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