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Less is more: lymphodepletion followed by hematopoietic stem cell transplant augments adoptive T-cell-based anti-tumor immunotherapy

Adoptive T-cell immunotherapy combined with non-myeloablative lymphodepletion has emerged as the most effective immunotherapy treatment for patients with metastatic melanoma (objective response rates of 50%). The mechanisms underlying this major advance in the field of immunotherapy include the elim...

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Detalhes bibliográficos
Main Authors: Wrzesinski, Claudia, Restifo, Nicholas P
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254579/
https://ncbi.nlm.nih.gov/pubmed/15766681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2005.02.002
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