Personalized Cell Transfer Immunotherapy for B-Cell Malignancies and Solid Cancers

Por Rosenberg, Steven A, Kochenderfer, James N
Publicado em 2011

Toxicities of chimeric antigen receptor T cells: recognition and management

Por Brudno, Jennifer N., Kochenderfer, James N.
Publicado no Blood (2016)

Vaccination regimens incorporating CpG-containing oligodeoxynucleotides and IL-2 generate antigen-specific antitumor immunity from T-cell populations undergoing homeostatic periphe...

Por Kochenderfer, James N., Simpson, Jessica L., Chien, Christopher D., Gress, Ronald E.
Publicado em 2007

Maximizing CD8(+) T cell Responses Elicited by Peptide Vaccines Containing CpG Oligodeoxynucleotides

Por Kochenderfer, James N., Chien, Christopher D., Simpson, Jessica L., Gress, Ronald E.
Publicado em 2007

Pigmented villonodular synovitis mimics metastases on fluorine 18 fluorodeoxyglucose position emission tomography-computed tomography

Por Elumogo, Comfort O., Kochenderfer, James N., Civelek, A. Cahid, Bluemke, David A.
Publicado no Quant Imaging Med Surg (2016)

Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells

Por Kochenderfer, James N., Yu, Zhiya, Frasheri, Dorina, Restifo, Nicholas P., Rosenberg, Steven A.
Publicado em 2010

Murine allogeneic CD19 CAR T cells harbor potent antileukemic activity but have the potential to mediate lethal GVHD

Por Jacoby, Elad, Yang, Yinmeng, Qin, Haiying, Chien, Christopher D., Kochenderfer, James N., Fry, Terry J.
Publicado no Blood (2016)

Construction and Pre-clinical Evaluation of an Anti-CD19 Chimeric Antigen Receptor

Por Kochenderfer, James N., Feldman, Steven A., Zhao, Yangbing, Xu, Hui, Black, Mary A., Morgan, Richard A., Wilson, Wyndham H., Rosenberg, Steven A.
Publicado em 2009

Use of the piggyBac Transposon to Create Stable Packaging Cell Lines for the Production of Clinical-Grade Self-Inactivating γ-Retroviral Vectors

Por Feldman, Steven A., Xu, Hui, Black, Mary A., Park, Tristen S., Robbins, Paul F., Kochenderfer, James N., Morgan, Richard A., Rosenberg, Steven A.
Publicado em 2014

B-cell Maturation Antigen is a Promising Target for Adoptive T-cell Therapy of Multiple Myeloma

Por Carpenter, Robert O., Evbuomwan, Moses O., Pittaluga, Stefania, Rose, Jeremy J., Raffeld, Mark, Yang, Shicheng, Gress, Ronald E., Hakim, Frances T., Kochenderfer, James N.
Publicado em 2013

Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19

Por Kochenderfer, James N., Wilson, Wyndham H., Janik, John E., Dudley, Mark E., Stetler-Stevenson, Maryalice, Feldman, Steven A., Maric, Irina, Raffeld, Mark, Nathan, Debbie-Ann N., Lanier, Brock J., Morgan, Richard A., Rosenberg, Steven A.
Publicado em 2010

Rapid Production of Clinical-Grade Gammaretroviral Vectors in Expanded Surface Roller Bottles Using a “Modified” Step-Filtration Process for Clearance of Packaging Cells

Por Feldman, Steven A., Goff, Stephanie L., Xu, Hui, Black, Mary A., Kochenderfer, James N., Johnson, Laura A., Yang, James C., Wang, Qiong, Parkhurst, Maria R., Cross, Scott, Morgan, Richard A., Cornetta, Kenneth, Rosenberg, Steven A.
Publicado em 2011

IL-12-conditioning improves retrovirally-mediated transduction efficiency of CD8(+) T cells

Por Andrijauskaite, Kristina, Suriano, Samantha, Cloud, Colleen A., Li, Mingli, Kesarwani, Pravin, Stefanik, Leah S., Moxley, Kelly M., Salem, Mohamed L, Garrett-Mayer, Elizabeth, Paulos, Chrystal M., Mehrotra, Shikhar, Kochenderfer, James N., Cole, David J., Rubinstein, Mark P.
Publicado no Cancer Gene Ther (2015)

Generation of clinical-grade CD19-specific CAR-modified CD8(+) memory stem cells for the treatment of human B-cell malignancies

Por Sabatino, Marianna, Hu, Jinhui, Sommariva, Michele, Gautam, Sanjivan, Fellowes, Vicki, Hocker, James D., Dougherty, Sean, Qin, Haiying, Klebanoff, Christopher A., Fry, Terry J., Gress, Ronald E., Kochenderfer, James N., Stroncek, David F., Ji, Yun, Gattinoni, Luca
Publicado no Blood (2016)

T cells expressing an anti–B-cell maturation antigen chimeric antigen receptor cause remissions of multiple myeloma

Por Ali, Syed Abbas, Shi, Victoria, Maric, Irina, Wang, Michael, Stroncek, David F., Rose, Jeremy J., Brudno, Jennifer N., Stetler-Stevenson, Maryalice, Feldman, Steven A., Hansen, Brenna G., Fellowes, Vicki S., Hakim, Frances T., Gress, Ronald E., Kochenderfer, James N.
Publicado no Blood (2016)

Versatile strategy for controlling the specificity and activity of engineered T cells

Por Ma, Jennifer S. Y., Kim, Ji Young, Kazane, Stephanie A., Choi, Sei-hyun, Yun, Hwa Young, Kim, Min Soo, Rodgers, David T., Pugh, Holly M., Singer, Oded, Sun, Sophie B., Fonslow, Bryan R., Kochenderfer, James N., Wright, Timothy M., Schultz, Peter G., Young, Travis S., Kim, Chan Hyuk, Cao, Yu
Publicado no Proc Natl Acad Sci U S A (2016)

B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells

Por Kochenderfer, James N., Dudley, Mark E., Feldman, Steven A., Wilson, Wyndham H., Spaner, David E., Maric, Irina, Stetler-Stevenson, Maryalice, Phan, Giao Q., Hughes, Marybeth S., Sherry, Richard M., Yang, James C., Kammula, Udai S., Devillier, Laura, Carpenter, Robert, Nathan, Debbie-Ann N., Morgan, Richard A., Laurencot, Carolyn, Rosenberg, Steven A.
Publicado em 2012

Allogeneic T Cells That Express an Anti-CD19 Chimeric Antigen Receptor Induce Remissions of B-Cell Malignancies That Progress After Allogeneic Hematopoietic Stem-Cell Transplantati...

Por Brudno, Jennifer N., Somerville, Robert P.T., Shi, Victoria, Rose, Jeremy J., Halverson, David C., Fowler, Daniel H., Gea-Banacloche, Juan C., Pavletic, Steven Z., Hickstein, Dennis D., Lu, Tangying L., Feldman, Steven A., Iwamoto, Alexander T., Kurlander, Roger, Maric, Irina, Goy, Andre, Hansen, Brenna G., Wilder, Jennifer S., Blacklock-Schuver, Bazetta, Hakim, Frances T., Rosenberg, Steven A., Gress, Ronald E., Kochenderfer, James N.
Publicado no J Clin Oncol (2016)

Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation

Por Kochenderfer, James N., Dudley, Mark E., Carpenter, Robert O., Kassim, Sadik H., Rose, Jeremy J., Telford, William G., Hakim, Frances T., Halverson, David C., Fowler, Daniel H., Hardy, Nancy M., Mato, Anthony R., Hickstein, Dennis D., Gea-Banacloche, Juan C., Pavletic, Steven Z., Sportes, Claude, Maric, Irina, Feldman, Steven A., Hansen, Brenna G., Wilder, Jennifer S., Blacklock-Schuver, Bazetta, Jena, Bipulendu, Bishop, Michael R., Gress, Ronald E., Rosenberg, Steven A.
Publicado em 2013

Chemotherapy-Refractory Diffuse Large B-Cell Lymphoma and Indolent B-Cell Malignancies Can Be Effectively Treated With Autologous T Cells Expressing an Anti-CD19 Chimeric Antigen R...

Por Kochenderfer, James N., Dudley, Mark E., Kassim, Sadik H., Somerville, Robert P.T., Carpenter, Robert O., Stetler-Stevenson, Maryalice, Yang, James C., Phan, Giao Q., Hughes, Marybeth S., Sherry, Richard M., Raffeld, Mark, Feldman, Steven, Lu, Lily, Li, Yong F., Ngo, Lien T., Goy, Andre, Feldman, Tatyana, Spaner, David E., Wang, Michael L., Chen, Clara C., Kranick, Sarah M., Nath, Avindra, Nathan, Debbie-Ann N., Morton, Kathleen E., Toomey, Mary Ann, Rosenberg, Steven A.
Publicado no J Clin Oncol (2015)