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Construction and Pre-clinical Evaluation of an Anti-CD19 Chimeric Antigen Receptor
T cells can be engineered to express the genes of chimeric antigen receptors (CARs) that recognize tumor-associated antigens. We constructed and compared two CARs that contained a single chain variable region moiety (scFv) that recognized CD19. One CAR contained the signaling moiety of the 4-1BB mol...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747302/ https://ncbi.nlm.nih.gov/pubmed/19561539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3181ac6138 |
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