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Treating B-cell cancer with T cells expressing anti-CD19 chimeric antigen receptors
Most B-cell malignancies express CD19, and a majority of patients with B-cell malignancies are not cured by current standard therapies. Chimeric antigen receptors (CARs) are fusion proteins consisting of antigen recognition moieties and T-cell activation domains. T cells can be genetically modified...
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| Publicado no: | Nat Rev Clin Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6322669/ https://ncbi.nlm.nih.gov/pubmed/23546520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2013.46 |
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