From Lipoproteins to Chondrocytes: A Brief Summary of the European Medicines Agency's Regulatory Guidelines for Advanced Therapy Medicinal Products

Por Kassim, Sadik H., Somerville, Robert P.T.
Publicado em 2013

Gene therapy for dyslipidemia: a review of gene replacement and gene inhibition strategies

Por Kassim, Sadik H, Wilson, James M, Rader, Daniel J
Publicado em 2010

In Vivo Ablation of CD11c-Positive Dendritic Cells Increases Susceptibility to Herpes Simplex Virus Type 1 Infection and Diminishes NK and T-Cell Responses

Por Kassim, Sadik H., Rajasagi, Naveen K., Zhao, Xiangyi, Chervenak, Robert, Jennings, Stephen R.
Publicado em 2006

Identification and functional characterization in vivo of a novel splice variant of LDLR in rhesus macaques

Por Kassim, Sadik H., Vandenberghe, Luk H., Hovhannisyan, Ruben, Wilson, James M., Rader, Daniel J.
Publicado em 2011

CD4(+) T Cells Are Required for the Priming of CD8(+) T Cells following Infection with Herpes Simplex Virus Type 1

Por Rajasagi, Naveen K., Kassim, Sadik H., Kollias, Christina M., Zhao, Xiangyi, Chervenak, Robert, Jennings, Stephen R.
Publicado em 2009

Dendritic Cells Are Required for Optimal Activation of Natural Killer Functions following Primary Infection with Herpes Simplex Virus Type 1

Por Kassim, Sadik H., Rajasagi, Naveen K., Ritz, Barry W., Pruett, Stephen B., Gardner, Elizabeth M., Chervenak, Robert, Jennings, Stephen R.
Publicado em 2009

Adeno-Associated Virus Serotype 8 Gene Therapy Leads to Significant Lowering of Plasma Cholesterol Levels in Humanized Mouse Models of Homozygous and Heterozygous Familial Hypercho...

Por Kassim, Sadik H., Li, Hui, Bell, Peter, Somanathan, Suryanarayan, Lagor, William, Jacobs, Frank, Billheimer, Jeffrey, Wilson, James M., Rader, Daniel J.
Publicado em 2013

Gene Therapy in a Humanized Mouse Model of Familial Hypercholesterolemia Leads to Marked Regression of Atherosclerosis

Por Kassim, Sadik H., Li, Hui, Vandenberghe, Luk H., Hinderer, Christian, Bell, Peter, Marchadier, Dawn, Wilson, Aisha, Cromley, Debra, Redon, Valeska, Yu, Hongwei, Wilson, James M., Rader, Daniel J.
Publicado em 2010

Biodistribution of AAV8 Vectors Expressing Human Low-Density Lipoprotein Receptor in a Mouse Model of Homozygous Familial Hypercholesterolemia

Por Chen, Shu-Jen, Sanmiguel, Julio, Lock, Martin, McMenamin, Deirdre, Draper, Christine, Limberis, Maria P., Kassim, Sadik H., Somanathan, Suryanarayan, Bell, Peter, Johnston, Julie C., Rader, Daniel J., Wilson, James M.
Publicado em 2013

Single-cell multiplexed cytokine profiling of CD19 CAR-T cells reveals a diverse landscape of polyfunctional antigen-specific response

Por Xue, Qiong, Bettini, Emily, Paczkowski, Patrick, Ng, Colin, Kaiser, Alaina, McConnell, Timothy, Kodrasi, Olja, Quigley, Máire F., Heath, James, Fan, Rong, Mackay, Sean, Dudley, Mark E., Kassim, Sadik H., Zhou, Jing
Publicado no J Immunother Cancer (2017)

Tumor Infiltrating Lymphocytes Genetically Engineered with an Inducible Gene Encoding Interleukin-12 for the Immunotherapy of Metastatic Melanoma

Por Zhang, Ling, Morgan, Richard A., D.Beane, Joal, Zheng, Zhili, Dudley, Mark E., Kassim, Sadik H., Nahvi, Azam V., Ngo, Lien T., Sherry, Richard M., Phan, Giao Q., Hughes, Marybeth S., Kammula, Udai S., Feldman, Steven A., Toomey, Mary Ann, Kerkar, Sid. P., Restifo, Nicholas P., Yang, James C., Rosenberg, Steven A.
Publicado no Clin Cancer Res (2015)

Clinical scale zinc finger nuclease (ZFN)-driven gene-editing of PD-1 in tumor infiltrating lymphocytes (TIL) for the potential treatment of metastatic melanoma

Por Beane, Joal D, Lee, Gary K, Zheng, Zhili, Gandhi, Nimisha, Abate-Daga, Daniel, Bharathan, Mini, Black, Mary, Mendel, Matthew, Yu, Zhiya, Kassim, Sadik H, Chandran, Smita, Giedlin, Martin, Ando, Dale, Rebar, Ed, Reik, Andreas, Holmes, Michael, Gregory, Philip D, Restifo, Nicholas P, Rosenberg, Steven A, Morgan, Richard A, Feldman, Steven A
Publicado no J Immunother Cancer (2014)

A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T cell receptor: Long term follow up and correlates with response

Por Robbins, Paul F., Kassim, Sadik H., Tran, Thai Lan N., Crystal, Jessica S., Morgan, Richard A., Feldman, Steven A., Yang, James C., Dudley, Mark E., Wunderlich, John R., Sherry, Richard M., Kammula, Udai S., Hughes, Marybeth S., Restifo, Nicholas P., Raffeld, Mark, Lee, Chyi-Chia Richard, Li, Yong F., El-Gamil, Mona, Rosenberg, Steven A.
Publicado no Clin Cancer Res (2014)

Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation

Por Kochenderfer, James N., Dudley, Mark E., Carpenter, Robert O., Kassim, Sadik H., Rose, Jeremy J., Telford, William G., Hakim, Frances T., Halverson, David C., Fowler, Daniel H., Hardy, Nancy M., Mato, Anthony R., Hickstein, Dennis D., Gea-Banacloche, Juan C., Pavletic, Steven Z., Sportes, Claude, Maric, Irina, Feldman, Steven A., Hansen, Brenna G., Wilder, Jennifer S., Blacklock-Schuver, Bazetta, Jena, Bipulendu, Bishop, Michael R., Gress, Ronald E., Rosenberg, Steven A.
Publicado em 2013

Chemotherapy-Refractory Diffuse Large B-Cell Lymphoma and Indolent B-Cell Malignancies Can Be Effectively Treated With Autologous T Cells Expressing an Anti-CD19 Chimeric Antigen R...

Por Kochenderfer, James N., Dudley, Mark E., Kassim, Sadik H., Somerville, Robert P.T., Carpenter, Robert O., Stetler-Stevenson, Maryalice, Yang, James C., Phan, Giao Q., Hughes, Marybeth S., Sherry, Richard M., Raffeld, Mark, Feldman, Steven, Lu, Lily, Li, Yong F., Ngo, Lien T., Goy, Andre, Feldman, Tatyana, Spaner, David E., Wang, Michael L., Chen, Clara C., Kranick, Sarah M., Nath, Avindra, Nathan, Debbie-Ann N., Morton, Kathleen E., Toomey, Mary Ann, Rosenberg, Steven A.
Publicado no J Clin Oncol (2015)

Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia

Por Fraietta, Joseph A., Lacey, Simon F., Orlando, Elena J., Pruteanu-Malinici, Iulian, Gohil, Mercy, Lundh, Stefan, Boesteanu, Alina C., Wang, Yan, O’Connor, Roddy S., Hwang, Wei-Ting, Pequignot, Edward, Ambrose, David E., Zhang, Changfeng, Wilcox, Nicholas, Bedoya, Felipe, Dorfmeier, Corin, Chen, Fang, Tian, Lifeng, Parakandi, Harit, Gupta, Minnal, Young, Regina M., Johnson, F. Brad, Kulikovskaya, Irina, Liu, Li, Xu, Jun, Kassim, Sadik H., Davis, Megan M., Levine, Bruce L., Frey, Noelle V., Siegel, Donald L., Huang, Alexander C., Wherry, E. John, Bitter, Hans, Brogdon, Jennifer L., Porter, David L., June, Carl H., Melenhorst, J. Joseph
Publicado no Nat Med (2018)