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IL-12-conditioning improves retrovirally-mediated transduction efficiency of CD8(+) T cells
The ability to genetically modify T cells is a critical component to many immunotherapeutic strategies and research studies. However, the success of these approaches is often limited by transduction efficiency. Since retroviral vectors require cell division for integration, transduction efficiency i...
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| Publicado en: | Cancer Gene Ther |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4807400/ https://ncbi.nlm.nih.gov/pubmed/26182912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2015.28 |
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