IL-12-conditioning improves retrovirally-mediated transduction efficiency of CD8(+) T cells

The ability to genetically modify T cells is a critical component to many immunotherapeutic strategies and research studies. However, the success of these approaches is often limited by transduction efficiency. Since retroviral vectors require cell division for integration, transduction efficiency i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Gene Ther
Prif Awduron: Andrijauskaite, Kristina, Suriano, Samantha, Cloud, Colleen A., Li, Mingli, Kesarwani, Pravin, Stefanik, Leah S., Moxley, Kelly M., Salem, Mohamed L, Garrett-Mayer, Elizabeth, Paulos, Chrystal M., Mehrotra, Shikhar, Kochenderfer, James N., Cole, David J., Rubinstein, Mark P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807400/
https://ncbi.nlm.nih.gov/pubmed/26182912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2015.28
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