IL-12-conditioning improves retrovirally-mediated transduction efficiency of CD8(+) T cells

The ability to genetically modify T cells is a critical component to many immunotherapeutic strategies and research studies. However, the success of these approaches is often limited by transduction efficiency. Since retroviral vectors require cell division for integration, transduction efficiency i...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cancer Gene Ther
Main Authors: Andrijauskaite, Kristina, Suriano, Samantha, Cloud, Colleen A., Li, Mingli, Kesarwani, Pravin, Stefanik, Leah S., Moxley, Kelly M., Salem, Mohamed L, Garrett-Mayer, Elizabeth, Paulos, Chrystal M., Mehrotra, Shikhar, Kochenderfer, James N., Cole, David J., Rubinstein, Mark P.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807400/
https://ncbi.nlm.nih.gov/pubmed/26182912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2015.28
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker