Lack of p53 Augments Anti-Tumor Functions in Cytolytic T Cells

Repetitive stimulation of T cell receptor (TCR) with cognate antigen results in robust proliferation and expansion of the T cells, and also imprints them with replicative senescence signatures. Our previous studies have shown that life-span and anti-tumor function of T cells can be enhanced by inhib...

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Bibliografski detalji
Izdano u:Cancer Res
Glavni autori: Banerjee, Anirban, Thyagarajan, Krishnamurthy, Chatterjee, Shilpak, Chakraborty, Paramita, Kesarwani, Pravin, Soloshchenko, Myroslawa, Al-Hommrani, Mazen, Andrijauskaite, Kristina, Moxley, Kelly, Janakiraman, Harinarayanan, Scheffel, Matthew J., Helke, Kristi, Armenson, Kent, Palanisamy, Viswanathan, Rubinstein, Mark P., Mayer, Elizabeth-Garrett, Cole, David J., Paulos, Chrystal M., Christina-Voelkel-Johnson, Nishimura, Michael I., Mehrotra, Shikhar
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026612/
https://ncbi.nlm.nih.gov/pubmed/27466285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1798
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