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Interferon-Gamma (IFN-γ)-Mediated Retinal Ganglion Cell Death in Human Tyrosinase T Cell Receptor Transgenic Mouse

We have recently demonstrated the characterization of human tyrosinase TCR bearing h3T-A2 transgenic mouse model, which exhibits spontaneous autoimmune vitiligo and retinal dysfunction. The purpose of current study was to determine the role of T cells and IFN-γ in retina dysfunction and retinal gang...

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Bibliografiske detaljer
Main Authors: Husain, Shahid, Abdul, Yasir, Webster, Christine, Chatterjee, Shilpak, Kesarwani, Pravin, Mehrotra, Shikhar
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938457/
https://ncbi.nlm.nih.gov/pubmed/24586745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089392
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