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Blocking TCR restimulation induced necroptosis in adoptively transferred T cells improves tumor control
Advancements in adoptive cell transfer therapy (ACT) has led to the use of T cells engineered with tumor specific T cell receptors, which after rapid expansion can be obtained in sufficient numbers for treating patients. However, due to massive proliferation these cells are close to replicative sene...
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| Publicado en: | Oncotarget |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342484/ https://ncbi.nlm.nih.gov/pubmed/27750220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12674 |
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