Vaccination with poly(IC:LC) and peptide-pulsed autologous dendritic cells in patients with pancreatic cancer

BACKGROUND: Dendritic cells (DCs) enhance the quality of anti-tumor immune response in patients with cancer. Thus, we posit that DC-based immunotherapy, in conjunction with toll-like receptor (TLR)-3 agonist poly-ICLC, is a promising approach for harnessing immunity against metastatic or locally adv...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Mehrotra, Shikhar, Britten, Carolyn D., Chin, Steve, Garrett-Mayer, Elizabeth, Cloud, Colleen A., Li, Mingli, Scurti, Gina, Salem, Mohamed L., Nelson, Michelle H., Thomas, Melanie B., Paulos, Chrystal M., Salazar, Andres M., Nishimura, Michael I., Rubinstein, Mark P., Li, Zihai, Cole, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384142/
https://ncbi.nlm.nih.gov/pubmed/28388966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0459-2
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