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MOUSE MODEL FOR PRE-CLINICAL STUDY OF HUMAN CANCER IMMUNOTHERAPY

This unit describes protocols for developing tumors in mice including subcutaneous growth, pulmonary metastases of B16 melanoma, and spontaneous melanoma in B-Raf V600E/PTEN deletion transgenic mouse models. Two immunization methods to prevent B16 tumor growth are described using B16.GM-CSF and reco...

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Bibliographic Details
Published in:Curr Protoc Immunol
Main Authors: Ya, Zhiya, Hailemichael, Yared, Overwijk, Willem, Restifo, Nicholas
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361407/
https://ncbi.nlm.nih.gov/pubmed/25640991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142735.im2001s108
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