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Targeting neoantigens for cancer immunotherapy

Studies first carried out in the 1980s have demonstrated murine T cells can recognize mutated gene products, known as neoantigens, and that these T cells are capable of mediating tumor rejection. The first human tumor antigens isolated in the early 1990s were the products of non-mutated genes expres...

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Detalles Bibliográficos
Publicado en:Int Immunol
Main Authors: Lu, Yong-Chen, Robbins, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007611/
https://ncbi.nlm.nih.gov/pubmed/27208041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxw026
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