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Targeting neoantigens for cancer immunotherapy

Studies first carried out in the 1980s have demonstrated murine T cells can recognize mutated gene products, known as neoantigens, and that these T cells are capable of mediating tumor rejection. The first human tumor antigens isolated in the early 1990s were the products of non-mutated genes expres...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int Immunol
Prif Awduron: Lu, Yong-Chen, Robbins, Paul F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007611/
https://ncbi.nlm.nih.gov/pubmed/27208041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxw026
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