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Immune targets and neoantigens for cancer immunotherapy and precision medicine

Harnessing the immune system to eradicate malignant cells is becoming a most powerful new approach to cancer therapy. FDA approval of the immunotherapy-based drugs, sipuleucel-T (Provenge), ipilimumab (Yervoy, anti-CTLA-4), and more recently, the programmed cell death (PD)-1 antibody (pembrolizumab,...

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Detalles Bibliográficos
Publicado en:Cell Res
Autores principales: Wang, Rong-Fu, Wang, Helen Y
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223235/
https://ncbi.nlm.nih.gov/pubmed/28025978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.155
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