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Selection of CD8(+)PD-1(+) lymphocytes in fresh human melanomas enriches for tumor-reactive T-cells

CD8(+) Tumor infiltrating lymphocyte (TIL) in human melanomas express high levels of PD-1 and are functionally impaired. However, adoptive cell therapy using in vitro-expanded TIL can be a highly effective therapy for patients with advanced melanoma. This discrepancy led us to further analyze the CD...

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Detaylı Bibliyografya
Asıl Yazarlar: Inozume, Takashi, Hanada, Ken-ichi, Wang, Qiong J., Ahmadzadeh, Mojgan, Wunderlich, John R., Rosenberg, Steven A., Yang, James C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980947/
https://ncbi.nlm.nih.gov/pubmed/20948441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3181fad2b0
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