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Enrichment of CD8(+) Cells From Melanoma Tumor-infiltrating Lymphocyte Cultures Reveals Tumor Reactivity for Use in Adoptive Cell Therapy

Adoptive cell therapy (ACT) using tumor-infiltrating lymphocytes (TIL) for metastatic melanoma has shown objective response rates as high as 72%. The successful application of this therapy requires the selection of unique tumor-reactive lymphocyte cultures for each patient. This is a technically and...

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Bibliographische Detailangaben
Veröffentlicht in:J Immunother
Hauptverfasser: Prieto, Peter A., Durflinger, Katherine H., Wunderlich, John R., Rosenberg, Steven A., Dudley, Mark E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309789/
https://ncbi.nlm.nih.gov/pubmed/20463593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3181d367bd
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