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Verapamil Enhances the Antitumoral Efficacy of Oncolytic Adenoviruses

The therapeutic potential of oncolytic adenoviruses is limited by the rate of adenovirus release. Based on the observation that several viruses induce cell death and progeny release by disrupting intracellular calcium homeostasis, we hypothesized that the alteration in intracellular calcium concentr...

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Hlavní autoři: Gros, Alena, Puig, Cristina, Guedan, Sonia, Rojas, Juan José, Alemany, Ramon, Cascallo, Manel
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890100/
https://ncbi.nlm.nih.gov/pubmed/20179683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.22
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