Verapamil Enhances the Antitumoral Efficacy of Oncolytic Adenoviruses

The therapeutic potential of oncolytic adenoviruses is limited by the rate of adenovirus release. Based on the observation that several viruses induce cell death and progeny release by disrupting intracellular calcium homeostasis, we hypothesized that the alteration in intracellular calcium concentr...

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Main Authors: Gros, Alena, Puig, Cristina, Guedan, Sonia, Rojas, Juan José, Alemany, Ramon, Cascallo, Manel
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
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Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890100/
https://ncbi.nlm.nih.gov/pubmed/20179683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.22
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