Cancer regression and neurologic toxicity following anti-MAGE-A3 TCR gene therapy

Nine cancer patients were treated with adoptive cell therapy using autologous anti-MAGE-A3 TCR engineered T cells. Five patients experienced clinical regression of their cancers including two on-going responders. Beginning 1–2 days post-infusion, three patients (#’s 5, 7, and 8) experienced mental s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Morgan, Richard A., Chinnasamy, Nachimuthu, Abate-Daga, Daniel D, Gros, Alena, Robbins, Paul F., Zheng, Zhili, Feldman, Steven A., Yang, James C., Sherry, Richard M., Phan, Giao Q., Hughes, Marybeth S., Kammula, Udai S., Miller, Akemi D., Hessman, Crystal J., Stewart, Ashley A., Restifo, Nicholas P., Quezado, Martha M., Alimchandani, Meghna, Rosenberg, Avi Z., Nath, Avindra, Wang, Tongguang, Bielekova, Bibiana, Wuest, Simone C., Nirmala, Akula, McMahon, Francis J., Wilde, Susanne, Mosetter, Barbara, Schendel, Dolores J., Laurencot, Carolyn M., Rosenberg, Steven A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581823/
https://ncbi.nlm.nih.gov/pubmed/23377668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3182829903
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg