Cancer regression and neurologic toxicity following anti-MAGE-A3 TCR gene therapy

Nine cancer patients were treated with adoptive cell therapy using autologous anti-MAGE-A3 TCR engineered T cells. Five patients experienced clinical regression of their cancers including two on-going responders. Beginning 1–2 days post-infusion, three patients (#’s 5, 7, and 8) experienced mental s...

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Xehetasun bibliografikoak
Egile Nagusiak: Morgan, Richard A., Chinnasamy, Nachimuthu, Abate-Daga, Daniel D, Gros, Alena, Robbins, Paul F., Zheng, Zhili, Feldman, Steven A., Yang, James C., Sherry, Richard M., Phan, Giao Q., Hughes, Marybeth S., Kammula, Udai S., Miller, Akemi D., Hessman, Crystal J., Stewart, Ashley A., Restifo, Nicholas P., Quezado, Martha M., Alimchandani, Meghna, Rosenberg, Avi Z., Nath, Avindra, Wang, Tongguang, Bielekova, Bibiana, Wuest, Simone C., Nirmala, Akula, McMahon, Francis J., Wilde, Susanne, Mosetter, Barbara, Schendel, Dolores J., Laurencot, Carolyn M., Rosenberg, Steven A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581823/
https://ncbi.nlm.nih.gov/pubmed/23377668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3182829903
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