Osteosarcoma Genetics and Epigenetics: Emerging Biology and Candidate Therapies

由 Morrow, James J., Khanna, Chand
發表在 Crit Rev Oncog (2015)

Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression()()

由 Lizardo, Michael M., Morrow, James J., Miller, Tyler E., Hong, Ellen S., Ren, Ling, Mendoza, Arnulfo, Halsey, Charles H., Scacheri, Peter C., Helman, Lee J., Khanna, Chand
發表在 Neoplasia (2016)

mTOR inhibition mitigates enhanced mRNA translation associated with the metastatic phenotype of osteosarcoma cells in vivo

由 Morrow, James J., Mendoza, Arnulfo, Koyen, Allyson, Lizardo, Michael M., Ren, Ling, Waybright, Timothy J., Hansen, Ryan J., Gustafson, Daniel L., Zhou, Ming, Fan, Timothy M., Scacheri, Peter C., Khanna, Chand
發表在 Clin Cancer Res (2016)

Characterization of the metastatic phenotype of a panel of established osteosarcoma cells

由 Ren, Ling, Mendoza, Arnulfo, Zhu, Jack, Briggs, Joseph W., Halsey, Charles, Hong, Ellen S., Burkett, Sandra S., Morrow, James J., Lizardo, Michael M., Osborne, Tanasa, Li, Samuel Q., Luu, Hue H., Meltzer, Paul, Khanna, Chand
發表在 Oncotarget (2015)

Ex vivo screen identifies CDK12 as a metastatic vulnerability in osteosarcoma

由 Bayles, Ian, Krajewska, Malgorzata, Pontius, W. Dean, Saiakhova, Alina, Morrow, James J., Bartels, Cynthia, Lu, Jim, Faber, Zachary J., Fedorov, Yuriy, Hong, Ellen S., Karnuta, Jaret M., Rubin, Brian, Adams, Drew J., George, Rani E., Scacheri, Peter C.
發表在 J Clin Invest (2019)

Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome

由 Cohen, Andrea J., Saiakhova, Alina, Corradin, Olivia, Luppino, Jennifer M., Lovrenert, Katreya, Bartels, Cynthia F., Morrow, James J., Mack, Stephen C., Dhillon, Gursimran, Beard, Lydia, Myeroff, Lois, Kalady, Matthew F., Willis, Joseph, Bradner, James E., Keri, Ruth A., Berger, Nathan A., Pruett-Miller, Shondra M., Markowitz, Sanford D., Scacheri, Peter C.
發表在 Nat Commun (2017)

Type-1-cytokines synergize with oncogene inhibition to induce tumor growth arrest

由 Acquavella, Nicolas, Clever, David, Yu, Zhiya, Roelke-Parker, Melody, Palmer, Douglas C., Xi, Liqiang, Pflicke, Holger, Ji, Yun, Gros, Alena, Hanada, Ken-ichi, Goldlust, Ian S., Mehta, Gautam U., Klebanoff, Christopher A., Crompton, Joseph G., Sukumar, Madhusudhanan, Morrow, James J., Franco, Zulmarie, Gattinoni, Luca, Liu, Hui, Wang, Ena, Marincola, Francesco, Stroncek, David F., Lee, Chyi-Chia R., Raffeld, Mark, Bosenberg, Marcus W., Roychoudhuri, Rahul, Restifo, Nicholas P.
發表在 Cancer Immunol Res (2014)

Positively selected enhancer elements endow osteosarcoma cells with metastatic competence

由 Morrow, James J., Bayles, Ian, Funnell, Alister PW, Miller, Tyler E., Saiakhova, Alina, Lizardo, Michael M., Bartels, Cynthia F., Kapteijn, Maaike Y., Hung, Stevephen, Mendoza, Arnulfo, Dhillon, Gursimran, Chee, Daniel R., Myers, Jay T., Allen, Frederick, Gambarotti, Marco, Righi, Alberto, DiFeo, Analisa, Rubin, Brian P., Huang, Alex Y., Meltzer, Paul S., Helman, Lee J., Picci, Piero, Versteeg, Henri, Stamatoyannopolus, John, Khanna, Chand, Scacheri, Peter C.
發表在 Nat Med (2018)

Transcription elongation factors represent in vivo cancer dependencies in glioblastoma

由 Miller, Tyler E., Liau, Brian B., Wallace, Lisa C., Morton, Andrew R., Xie, Qi, Dixit, Deobrat, Factor, Daniel C., Kim, Leo J. Y., Morrow, James J., Wu, Qiulian, Mack, Stephen C., Hubert, Christopher G., Gillespie, Shawn M., Flavahan, William A., Hoffmann, Thomas, Thummalapalli, Rohit, Hemann, Michael T., Paddison, Patrick J., Horbinski, Craig M., Zuber, Johannes, Scacheri, Peter C., Bernstein, Bradley E., Tesar, Paul J., Rich, Jeremy N.
發表在 Nature (2017)

Therapeutic Targeting of Ependymoma as Informed by Oncogenic Enhancer Profiling

由 Mack, Stephen C., Pajtler, Kristian W., Chavez, Lukas, Okonechnikov, Konstantin, Bertrand, Kelsey C., Wang, Xiuxing, Erkek, Serap, Federation, Alexander, Song, Anne, Lee, Christine, Wang, Xin, McDonald, Laura, Morrow, James J., Saiakhova, Alina, Sin-Chan, Patrick, Wu, Qiulian, Michaelraj, Antony, Miller, Tyler E., Hubert, Christopher G., Ryzhova, Marina, Garzia, Livia, Donovan, Laura, Dombrowski, Stephen, Factor, Daniel C., Luu, Betty, Valentim, Claudia L.L., Gimple, Ryan C., Morton, Andrew, Kim, Leo, Prager, Briana C., Lee, John J.Y., Wu, Xiaochong, Zuccaro, Jennifer, Thompson, Yuan, de Borja López Holgado, Francisco, Reimand, Juri, Ke, Susan Q., Tropper, Adam, Lai, Sisi, Vijayarajah, Senthuran, Doan, Sylvia, Mahadev, Vaidehi, Miñan, Ana Fernandez, Gröbner, Susanne N., Lienhard, Matthias, Zapatka, Marc, Huang, Zhiqin, Aldape, Kenneth D., Carcaboso, Angel M., Houghton, Peter J., Keir, Stephen T., Milde, Till, Witt, Hendrik, Li, Yan, Li, Chao-Jun, Bian, Xiu-Wu, Jones, David T.W., Scott, Ian, Singh, Sheila K., Huang, Annie, Dirks, Peter B., Bouffet, Eric, Bradner, James E., Ramaswamy, Vijay, Jabado, Nada, Rutka, James T., Northcott, Paul A., Lupien, Mathieu, Lichter, Peter, Korshunov, Andrey, Scacheri, Peter C., Pfister, Stefan M., Kool, Marcel, Taylor, Michael D., Rich, Jeremy N.
發表在 Nature (2017)