Emerging Roles of Kruppel-Like Factor 6 and Kruppel-Like Factor 6 Splice Variant 1 in Ovarian Cancer Progression and Treatment

Por DiFeo, Analisa, Narla, Goutham, Martignetti, John A.
Publicado em 2009

Nucleo-Cytoplasmic Localization Domains Regulate Krüppel-Like Factor 6 (KLF6) Protein Stability and Tumor Suppressor Function

Por Rodríguez, Estefanía, Aburjania, Nana, Priedigkeit, Nolan M., DiFeo, Analisa, Martignetti, John A.
Publicado em 2010

Crowdsourcing Awareness: Exploration of the Ovarian Cancer Knowledge Gap through Amazon Mechanical Turk

Por Carter, Rebecca R., DiFeo, Analisa, Bogie, Kath, Zhang, Guo-Qiang, Sun, Jiayang
Publicado em 2014

A Functional Role for KLF6-SV1 in Lung Adenocarcinoma Prognosis and Chemotherapy Response

Por DiFeo, Analisa, Feld, Lauren, Rodriguez, Estefania, Wang, Christine, Beer, David G., Martignetti, John A., Narla, Goutham
Publicado em 2008

KLF6-SV1 Is a Novel Antiapoptotic Protein That Targets the BH3-Only Protein NOXA for Degradation and Whose Inhibition Extends Survival in an Ovarian Cancer Model

Por DiFeo, Analisa, Huang, Fei, Sangodkar, Jaya, Terzo, Esteban A., Leake, Devin, Narla, Goutham, Martignetti, John A.
Publicado em 2009

Altered glutamine metabolism in platinum resistant ovarian cancer

Por Hudson, Chantelle D., Savadelis, Alyssa, Nagaraj, Anil Belur, Joseph, Peronne, Avril, Stefanie, DiFeo, Analisa, Avril, Norbert
Publicado no Oncotarget (2016)

Targeted reduction of KLF6-SV1 restores chemotherapy sensitivity in resistant lung adenocarcinoma

Por Sangodkar, Jaya, DiFeo, Analisa, Feld, Lauren, Bromberg, Romina, Huang, Fei, Terzo, Esteban A., Choudhri, Aisha, Narla, Goutham
Publicado em 2009

Critical role of Wnt/β-catenin signaling in driving epithelial ovarian cancer platinum resistance

Por Nagaraj, Anil Belur, Joseph, Peronne, Kovalenko, Olga, Singh, Sareena, Armstrong, Amy, Redline, Raymond, Resnick, Kimberly, Zanotti, Kristine, Waggoner, Steven, DiFeo, Analisa
Publicado no Oncotarget (2015)

Ligand-dependent Corepressor (LCoR) Recruitment by Krüppel-like Factor 6 (KLF6) Regulates Expression of the Cyclin-dependent Kinase Inhibitor CDKN1A Gene

Por Calderon, Mario R., Verway, Mark, An, Beum-Soo, DiFeo, Analisa, Bismar, Tarek A., Ann, David K., Martignetti, John A., Shalom-Barak, Tali, White, John H.
Publicado em 2012

Cisplatin induces stemness in ovarian cancer

Por Wiechert, Andrew, Saygin, Caner, Thiagarajan, Praveena S., Rao, Vinay S., Hale, James S., Gupta, Nikhil, Hitomi, Masahiro, Nagaraj, Anil Belur, DiFeo, Analisa, Lathia, Justin D., Reizes, Ofer
Publicado no Oncotarget (2016)

Multiple Breast Cancer Cell-Lines Derived from a Single Tumor Differ in Their Molecular Characteristics and Tumorigenic Potential

Por Mosoyan, Goar, Nagi, Chandandeep, Marukian, Svetlana, Teixeira, Avelino, Simonian, Anait, Resnick-Silverman, Lois, DiFeo, Analisa, Johnston, Dean, Reynolds, Sandra R., Roses, Daniel F., Mosoian, Arevik
Publicado em 2013

Loss of Matrix Metalloproteinase-2 Amplifies Murine Toxin-Induced Liver Fibrosis by Upregulating Collagen I Expression

Por Radbill, Brian D., Gupta, Ritu, Ramirez, Maria Celeste M., DiFeo, Analisa, Martignetti, John A., Alvarez, Carlos E., Friedman, Scott L., Narla, Goutham, Vrabie, Raluca, Bowles, Robert, Saiman, Yedidya, Bansal, Meena B.
Publicado em 2010

Ribosome-inactivating proteins isolated from dietary bitter melon induce apoptosis and inhibit histone deacetylase-1 selectively in premalignant and malignant prostate cancer cells

Por Xiong, Su Dao, Yu, Kang, Liu, Xin Hua, Yin, Li Hui, Kirschenbaum, Alexander, Yao, Shen, Narla, Goutham, DiFeo, Analisa, Wu, Jian Buo, Yuan, Yong, Ho, Shuk-Mei, Lam, Ying Wai, Levine, Alice C.
Publicado em 2009

KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis

Por Narla, Goutham, DiFeo, Analisa, Fernandez, Yolanda, Dhanasekaran, Saravana, Huang, Fei, Sangodkar, Jaya, Hod, Eldad, Leake, Devin, Friedman, Scott L., Hall, Simon J., Chinnaiyan, Arul M., Gerald, William L., Rubin, Mark A., Martignetti, John A.
Publicado em 2008

Functional role of the KLF6 tumour suppressor gene in gastric cancer

Por Sangodkar, Jaya, Shi, Jiayan, DiFeo, Analisa, Schwartz, Rachel, Bromberg, Romina, Choudhri, Aisha, McClinch, Kim, Hatami, Raheleh, Scheer, Elias, Kremer-Tal, Sigal, Martignetti, John A, Hui, Alex, Leung, WK, Friedman, Scott L, Narla, Goutham
Publicado em 2008

KLF6-SV1 Drives Breast Cancer Metastasis and Is Associated with Poor Survival

Por Hatami, Raheleh, Sieuwerts, Anieta M., Izadmehr, Sudeh, Yao, Zhong, Qiao, Rui Fang, Papa, Luena, Look, Maxime P., Smid, Marcel, Ohlssen, Jessica, Levine, Alice C., Germain, Doris, Burstein, David, Kirschenbaum, Alexander, DiFeo, Analisa, Foekens, John A., Narla, Goutham
Publicado no Sci Transl Med (2013)

Targeting the FOXO1/KLF6 axis regulates EGFR signaling and treatment response

Por Sangodkar, Jaya, Dhawan, Neil S., Melville, Heather, Singh, Varan J., Yuan, Eric, Rana, Huma, Izadmehr, Sudeh, Farrington, Caroline, Mazhar, Sahar, Katz, Suzanna, Albano, Tara, Arnovitz, Pearlann, Okrent, Rachel, Ohlmeyer, Michael, Galsky, Matthew, Burstein, David, Zhang, David, Politi, Katerina, DiFeo, Analisa, Narla, Goutham
Publicado em 2012

microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial–mesenchymal transition

Por Parikh, Aditya, Lee, Christine, Joseph, Peronne, Marchini, Sergio, Baccarini, Alessia, Kolev, Valentin, Romualdi, Chiara, Fruscio, Robert, Shah, Hardik, Wang, Feng, Mullokandov, Gavriel, Fishman, David, D’Incalci, Maurizio, Rahaman, Jamal, Kalir, Tamara, Redline, Raymond W., Brown, Brian D., Narla, Goutham, DiFeo, Analisa
Publicado em 2014

Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation

Por Kremer-Tal, Sigal, Narla, Goutham, Chen, Yingbei, Hod, Eldad, DiFeo, Analisa, Yea, Steven, Lee, Ju-Seog, Schwartz, Myron, Thung, Swan N., Fiel, Isabel M., Banck, Michaela, Zimran, Eran, Thorgeirsson, Snorri S., Mazzaferro, Vincenzo, Bruix, Jordi, Martignetti, John A., Llovet, Josep M., Friedman, Scott L.
Publicado em 2006

Loss of MMP-2 disrupts skeletal and craniofacial development, and results in decreased bone mineralization, joint erosion, and defects in osteoblast and osteoclast growth

Por Mosig, Rebecca A., Dowling, Oonagh, DiFeo, Analisa, Ramirez, Maria Celeste M., Parker, Ian C., Abe, Etsuko, Diouri, Janane, Aqeel, Aida Al, Wylie, James D., Oblander, Samantha A., Madri, Joseph, Bianco, Paolo, Apte, Suneel S., Zaidi, Mone, Doty, Stephen B., Majeska, Robert J., Schaffler, Mitchell B., Martignetti, John A.
Publicado em 2007