Improved PCR Amplification of Broad Spectrum GC DNA Templates

by Guido, Nicholas, Starostina, Elena, Leake, Devin, Saaem, Ishtiaq
Published in PLoS One (2016)

Specificity and functionality of microRNA inhibitors

by Robertson, Barbara, Dalby, Andrew B, Karpilow, Jon, Khvorova, Anastasia, Leake, Devin, Vermeulen, Annaleen
Published 2010

Determination of a Screening Metric for High Diversity DNA Libraries

by Guido, Nicholas J., Handerson, Steven, Joseph, Elaine M., Leake, Devin, Kung, Li A.
Published in PLoS One (2016)

A complex containing CstF-64 and the SL2 snRNP connects mRNA 3′ end formation and trans-splicing in C. elegans operons

by Evans, Donald, Perez, Ismael, MacMorris, Margaret, Leake, Devin, Wilusz, Carol J., Blumenthal, Thomas
Published 2001

Synthesis, Biophysical Studies and RNA Interference Activity of RNA Having Three Consecutive Amide Linkages

by Tanui, Paul, Kennedy, Scott D., Lunstad, Benjamin D., Haas, Amanda, Leake, Devin, Rozners, Eriks
Published 2014

Functional Profiling Reveals Critical Role for miRNA in Differentiation of Human Mesenchymal Stem Cells

by Schoolmeesters, Angela, Eklund, Teresa, Leake, Devin, Vermeulen, Annaleen, Smith, Queta, Force Aldred, Shelley, Fedorov, Yuriy
Published 2009

Double-stranded regions are essential design components of potent inhibitors of RISC function

by Vermeulen, Annaleen, Robertson, Barbara, Dalby, Andrew B., Marshall, William S., Karpilow, Jon, Leake, Devin, Khvorova, Anastasia, Baskerville, Scott
Published 2007

KLF6-SV1 Is a Novel Antiapoptotic Protein That Targets the BH3-Only Protein NOXA for Degradation and Whose Inhibition Extends Survival in an Ovarian Cancer Model

by DiFeo, Analisa, Huang, Fei, Sangodkar, Jaya, Terzo, Esteban A., Leake, Devin, Narla, Goutham, Martignetti, John A.
Published 2009

Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs

by Mutisya, Daniel, Selvam, Chelliah, Lunstad, Benjamin D., Pallan, Pradeep S., Haas, Amanda, Leake, Devin, Egli, Martin, Rozners, Eriks
Published 2014

Induction of the interferon response by siRNA is cell type– and duplex length–dependent

by Reynolds, Angela, Anderson, Emily M., Vermeulen, Annaleen, Fedorov, Yuriy, Robinson, Kathryn, Leake, Devin, Karpilow, Jon, Marshall, William S., Khvorova, Anastasia
Published 2006

Off-target effects by siRNA can induce toxic phenotype

by Fedorov, Yuriy, Anderson, Emily M., Birmingham, Amanda, Reynolds, Angela, Karpilow, Jon, Robinson, Kathryn, Leake, Devin, Marshall, William S., Khvorova, Anastasia
Published 2006

Experimental validation of the importance of seed complement frequency to siRNA specificity

by Anderson, Emily M., Birmingham, Amanda, Baskerville, Scott, Reynolds, Angela, Maksimova, Elena, Leake, Devin, Fedorov, Yuriy, Karpilow, Jon, Khvorova, Anastasia
Published 2008

Silencing of Reporter Gene Expression in Skin Using siRNAs and Expression of Plasmid DNA Delivered by a Soluble Protrusion Array Device (PAD)

by Gonzalez-Gonzalez, Emilio, Speaker, Tycho J, Hickerson, Robyn P, Spitler, Ryan, Flores, Manuel A, Leake, Devin, Contag, Christopher H, Kaspar, Roger L
Published 2010

In Vivo Sustained Release of siRNA from Solid Lipid Nanoparticles

by Lobovkina, Tatsiana, Jacobson, Gunilla B., Gonzalez, Emilio Gonzalez, Hickerson, Robyn P., Leake, Devin, Kaspar, Roger L., Contag, Christopher H., Zare, Richard N.
Published 2011

Inhibition of CD44 Gene Expression in Human Skin Models, Using Self-Delivery Short Interfering RNA Administered by Dissolvable Microneedle Arrays

by Lara, Maria Fernanda, González-González, Emilio, Speaker, Tycho J., Hickerson, Robyn P., Leake, Devin, Milstone, Leonard M., Contag, Christopher H., Kaspar, Roger L.
Published 2012

Stability Study of Unmodified siRNA and Relevance to Clinical Use

by Hickerson, Robyn P., Vlassov, Alexander V., Wang, Qian, Leake, Devin, Ilves, Heini, Gonzalez-Gonzalez, Emilio, Contag, Christopher H., Johnston, Brian H., Kaspar, Roger L.
Published 2008

In Vivo Imaging of Human and Mouse Skin with a Handheld Dual-Axis Confocal Fluorescence Microscope

by Ra, Hyejun, Piyawattanametha, Wibool, Gonzalez-Gonzalez, Emilio, Mandella, Michael J., Kino, Gordon S., Solgaard, Olav, Leake, Devin, Kaspar, Roger L., Oro, Anthony, Contag, Christopher H.
Published 2010

Optimized PCR Conditions and Increased shRNA Fold Representation Improve Reproducibility of Pooled shRNA Screens

by Strezoska, Žaklina, Licon, Abel, Haimes, Josh, Spayd, Katie Jansen, Patel, Kruti M., Sullivan, Kevin, Jastrzebski, Katarzyna, Simpson, Kaylene J., Leake, Devin, van Brabant Smith, Anja, Vermeulen, Annaleen
Published 2012

Gene Silencing in Skin After Deposition of Self-Delivery siRNA With a Motorized Microneedle Array Device

by Hickerson, Robyn P, Wey, Winston C, Rimm, David L, Speaker, Tycho, Suh, Susie, Flores, Manuel A, Gonzalez-Gonzalez, Emilio, Leake, Devin, Contag, Christopher H, Kaspar, Roger L
Published 2013

Position-specific chemical modification of siRNAs reduces “off-target” transcript silencing

by Jackson, Aimee L., Burchard, Julja, Leake, Devin, Reynolds, Angela, Schelter, Janell, Guo, Jie, Johnson, Jason M., Lim, Lee, Karpilow, Jon, Nichols, Kim, Marshall, William, Khvorova, Anastasia, Linsley, Peter S.
Published 2006