Specificity and functionality of microRNA inhibitors

BACKGROUND: Micro(mi)RNAs regulate gene expression through translational attenuation and messenger (m)RNA degradation, and are associated with differentiation, homeostasis and disease. Natural miRNA target recognition is determined primarily by perfect complementarity in a seed region (nucleotide po...

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Detalhes bibliográficos
Main Authors: Robertson, Barbara, Dalby, Andrew B, Karpilow, Jon, Khvorova, Anastasia, Leake, Devin, Vermeulen, Annaleen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864222/
https://ncbi.nlm.nih.gov/pubmed/20359337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-907X-1-10
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