Context-specific microRNA analysis: identification of functional microRNAs and their mRNA targets

MicroRNAs (miRs) function primarily as post-transcriptional negative regulators of gene expression through binding to their mRNA targets. Reliable prediction of a miR’s targets is a considerable bioinformatic challenge of great importance for inferring the miR’s function. Sequence-based prediction a...

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Bibliografiske detaljer
Main Authors: Bossel Ben-Moshe, Noa, Avraham, Roi, Kedmi, Merav, Zeisel, Amit, Yitzhaky, Assif, Yarden, Yosef, Domany, Eytan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Computational Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505984/
https://ncbi.nlm.nih.gov/pubmed/22977182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks841
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