Resultados da pesquisa por Autor

1

The Pairing Geometry of the Hydrophobic Thymine Analog 2,4-Difluorotoluene in Duplex DNA as Analyzed by X-ray Crystallography

The Pairing Geometry of the Hydrophobic Thymine Analog 2,4-Difluorotoluene in Duplex DNA as Analyzed by X-ray Crystallography

Por Pallan, Pradeep S., Egli, Martin
Publicado em 2009

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2

Crystallographic Studies of Chemically Modified Nucleic Acids: A Backward Glance

Crystallographic Studies of Chemically Modified Nucleic Acids: A Backward Glance

Por Egli, Martin, Pallan, Pradeep S.
Publicado em 2010

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3

The many twists and turns of DNA: template, telomere, tool and target

The many twists and turns of DNA: template, telomere, tool and target

Por Egli, Martin, Pallan, Pradeep S.
Publicado em 2010

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4

Insights into RNA/DNA hybrid recognition and processing by RNase H from the crystal structure of a non-specific enzyme-dsDNA complex

Insights into RNA/DNA hybrid recognition and processing by RNase H from the crystal structure of a non-specific enzyme-dsDNA complex

Por Pallan, Pradeep S., Egli, Martin
Publicado em 2008

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5

The Conformationally Constrained N-Methanocarba-dT Analog Adopts an Unexpected C4'-exo Sugar Pucker in the Structure of a DNA Hairpin

The Conformationally Constrained N-Methanocarba-dT Analog Adopts an Unexpected C4'-exo Sugar Pucker in the Structure of a DNA Hairpin

Por Pallan, Pradeep S., Marquez, Victor E., Egli, Martin
Publicado em 2012

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6

Syntheses of 4′-thioribonucleosides and thermodynamic stability and crystal structure of RNA oligomers with incorporated 4′-thiocytosine

Syntheses of 4′-thioribonucleosides and thermodynamic stability and crystal structure of RNA oligomers with incorporated 4′-thiocytosine

Por Haeberli, Peter, Berger, Imre, Pallan, Pradeep S., Egli, Martin
Publicado em 2005

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7

Backbone-base inclination as a fundamental determinant of nucleic acid self- and cross-pairing

Backbone-base inclination as a fundamental determinant of nucleic acid self- and cross-pairing

Por Pallan, Pradeep S., Lubini, Paolo, Bolli, Martin, Egli, Martin
Publicado em 2007

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8

Effects of N(2),N(2)-dimethylguanosine on RNA structure and stability: Crystal structure of an RNA duplex with
tandem m(2)
(2)G:A pairs

Effects of N(2),N(2)-dimethylguanosine on RNA structure and stability: Crystal structure of an RNA duplex with tandem m(2) (2)G:A pairs

Por Pallan, Pradeep S., Kreutz, Christoph, Bosio, Silvia, Micura, Ronald, Egli, Martin
Publicado em 2008

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9

Effects of N(2),N(2)-dimethylguanosine on RNA structure and stability: Crystal structure of an RNA duplex with tandem m(2)
(2)G:A pairs

Effects of N(2),N(2)-dimethylguanosine on RNA structure and stability: Crystal structure of an RNA duplex with tandem m(2) (2)G:A pairs

Por Pallan, Pradeep S., Kreutz, Christoph, Bosio, Silvia, Micura, Ronald, Egli, Martin
Publicado em 2008

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10

Synthesis, Duplex Stabilization and Structural Properties of a Fluorinated Carbocyclic LNA Analog

Synthesis, Duplex Stabilization and Structural Properties of a Fluorinated Carbocyclic LNA Analog

Por Seth, Punit P., Pallan, Pradeep S., Swayze, Eric E., Egli, Martin
Publicado em 2012

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11

The Enzyme‐Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid

The Enzyme‐Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid

Por Jovanovic, Dejana, Tremmel, Peter, Pallan, Pradeep S., Egli, Martin, Richert, Clemens
Publicado no Angew Chem Int Ed Engl (2020)

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12

Comparative analysis of inosine-substituted duplex DNA by circular dichroism and X-ray crystallography

Comparative analysis of inosine-substituted duplex DNA by circular dichroism and X-ray crystallography

Por Peters, Justin P., Kowal, Ewa A., Pallan, Pradeep S., Egli, Martin, Maher, L. James
Publicado no J Biomol Struct Dyn (2017)

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13

Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Nonionic Modifications Better than DNA

Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Nonionic Modifications Better than DNA

Por Kolarovic, Andrej, Schweizer, Emma, Greene, Emily, Gironda, Mark, Pallan, Pradeep S., Egli, Martin, Rozners, Eriks
Publicado em 2009

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14

A Conformational Transition in the Structure of a 2′-Thiomethyl-Modified DNA Visualized at High Resolution

A Conformational Transition in the Structure of a 2′-Thiomethyl-Modified DNA Visualized at High Resolution

Por Pallan, Pradeep S., Prakash, Thazha P., Li, Feng, Eoff, Robert L., Manoharan, Muthiah, Egli, Martin
Publicado em 2009

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15

Insights from Crystal Structures into the Opposite Effects on RNA Affinity by the S- and R-6′-Methyl Backbone Modifications of 3′-Fluoro Hexitol Nucleic Acid (FHNA)()

Insights from Crystal Structures into the Opposite Effects on RNA Affinity by the S- and R-6′-Methyl Backbone Modifications of 3′-Fluoro Hexitol Nucleic Acid (FHNA)()

Por Pallan, Pradeep S., Yu, Jinghua, Allerson, Charles R., Swayze, Eric E., Seth, Punit, Egli, Martin
Publicado em 2011

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16

Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs

Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs

Por Patra, Amritraj, Harp, Joel, Pallan, Pradeep S., Zhao, Linlin, Abramov, Mikhail, Herdewijn, Piet, Egli, Martin
Publicado em 2013

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17

Research Resource: Correlating Human Cytochrome P450 21A2 Crystal Structure and Phenotypes of Mutations in Congenital Adrenal Hyperplasia

Research Resource: Correlating Human Cytochrome P450 21A2 Crystal Structure and Phenotypes of Mutations in Congenital Adrenal Hyperplasia

Por Pallan, Pradeep S., Lei, Li, Wang, Chunxue, Waterman, Michael R., Guengerich, F. Peter, Egli, Martin
Publicado no Mol Endocrinol (2015)

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18

Unexpected origins of the enhanced pairing affinity of 2′-fluoro-modified RNA

Unexpected origins of the enhanced pairing affinity of 2′-fluoro-modified RNA

Por Pallan, Pradeep S., Greene, Emily M., Jicman, Paul Andrei, Pandey, Rajendra K., Manoharan, Muthiah, Rozners, Eriks, Egli, Martin
Publicado em 2011

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19

Altering the Electrostatic Potential in the Major Groove: Thermodynamic and Structural Characterization of 7-Deaza-2′-deoxyadenosine:dT Base Pairing in DNA

Altering the Electrostatic Potential in the Major Groove: Thermodynamic and Structural Characterization of 7-Deaza-2′-deoxyadenosine:dT Base Pairing in DNA

Por Kowal, Ewa A., Ganguly, Manjori, Pallan, Pradeep S., Marky, Luis A., Gold, Barry, Egli, Martin, Stone, Michael P.
Publicado em 2011

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20

Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs

Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs

Por Mutisya, Daniel, Selvam, Chelliah, Lunstad, Benjamin D., Pallan, Pradeep S., Haas, Amanda, Leake, Devin, Egli, Martin, Rozners, Eriks
Publicado em 2014

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