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Comparative analysis of inosine-substituted duplex DNA by circular dichroism and X-ray crystallography

Leveraging structural biology tools, we report the results of experiments seeking to determine if the different mechanical properties of DNA polymers with base analog substitutions can be attributed, at least in part, to induced changes from classical B-form DNA. The underlying hypothesis is that di...

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Detalhes bibliográficos
Publicado no:J Biomol Struct Dyn
Main Authors: Peters, Justin P., Kowal, Ewa A., Pallan, Pradeep S., Egli, Martin, Maher, L. James
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251417/
https://ncbi.nlm.nih.gov/pubmed/28818035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2017.1369164
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