Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics

Adoptive cell therapy (ACT) using autologous tumor-infiltrating lymphocytes (TIL) can result in complete regression of advanced cancer in some patients, but the efficacy of this potentially curative therapy might be limited by poor persistence of TIL after adoptive-transfer. Pharmacologic inhibition...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancer Res
मुख्य लेखकों: Crompton, Joseph G., Sukumar, Madhusudhanan, Roychoudhuri, Rahul, Clever, David, Gros, Alena, Eil, Robert, Tran, Eric, Hanada, Ken-ichi, Yu, Zhiya, Palmer, Douglas C., Kerkar, Sid P., Michalek, Ryan D., Upham, Trevor, Leonardi, Anthony, Aquavella, Nicholas, Wang, Ena, Marincola, Francesco M., Gattinoni, Luca, Muranski, Pawel, Sundrud, Mark S., Klebanoff, Christopher A., Rosenberg, Steven A., Fearon, Douglas T., Restifo, Nicholas P.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384335/
https://ncbi.nlm.nih.gov/pubmed/25432172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2277
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