Mitochondrial membrane potential identifies cells with enhanced stemness for cellular therapy

Long-term survival and anti-tumor immunity of adoptively-transferred CD8(+) T cells is dependent on their metabolic fitness, but approaches to isolate therapeutic T cells based on metabolic features are not well established. Here we utilized a lipophilic cationic dye tetramethylrhodamine methyl este...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Sukumar, Madhusudhanan, Liu, Jie, Mehta, Gautam U., Patel, Shashank J., Roychoudhuri, Rahul, Crompton, Joseph G., Klebanoff, Christopher A., Ji, Yun, Li, Peng, Yu, Zhiya, Whitehill, Greg D., Clever, David, Eil, Robert L, Palmer, Douglas, Mitra, Suman, Rao, Mahadev, Keyvanfar, Keyvan, Schrump, David, Wang, Ena, Marincola, Francesco, Gattinoni, Luca, Leonard, Warren J, Muranski, Pawel, Finkel, Toren, Restifo, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747432/
https://ncbi.nlm.nih.gov/pubmed/26674251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.11.002
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